BIOCHEMICAL PHARMACOLOGY AND DRUG DESIGN
Our department uses a state-of-the-art and highly efficient technological platform
for drug design. It is not only applied to screening and evaluation of biological
activity, but also for estimation of diverse pharmacological parameters of new
chemical entities and natural compounds. We aim at the development of innovative
therapeutic and diagnostic agents. The research activities of the Department spans
across the following main topics: target-directed synthesis and characterization
of biologically active molecules; Design and synthesis of molecular probes – new
hybrid structures or precursors for radiolabeling with subsequent biological and
diagnostic applications; Development of prodrugs – modified molecules with improved
bioavailability and reduced risk of toxicity.
