{"id":2364,"date":"2020-06-11T07:55:19","date_gmt":"2020-06-11T05:55:19","guid":{"rendered":"http:\/\/www.bio21.bas.bg\/ippg\/en\/?page_id=2364"},"modified":"2020-06-11T08:03:16","modified_gmt":"2020-06-11T06:03:16","slug":"vasilisa-manova","status":"publish","type":"page","link":"http:\/\/www.bio21.bas.bg\/ippg\/en\/?page_id=2364","title":{"rendered":"Vasilisa Manova"},"content":{"rendered":"<table width=\"550\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-10271\" style=\"border: 1px solid grey; border-radius: 9px; box-shadow: 1px 1px 3px #717070;\" src=\"http:\/\/www.bio21.bas.bg\/ippg\/bg\/wp-content\/uploads\/2020\/06\/manova-v.jpg\" alt=\"\" width=\"200\" height=\"200\" \/><\/td>\n<td style=\"text-align: center;\" width=\"310\">\n<h5>Vasilissa Manova, Assistant Professor, PhD<\/h5>\n<p>Building 21<br \/>\nOffice 106, Lab 211, 221<br \/>\nPhone: +359 (2) 979 2678<br \/>\n\u0415-mail: <a href=\"mailto:vmanova@bas.bg\">vmanova@bas.bg<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>Professional interests<\/h3>\n<p style=\"text-align: justify;\">Molecular mechanisms of plant stress response to DNA damage. Activity and genetic control of DNA repair in plants, Radiation-induced stress response in barley. Molecular mechanisms of seed ageing. Radiation-induced DNA damage and repair in mammalian cells. Molecular identification and genotyping of fungal pathogens in cereals and horticultural plants.<\/p>\n<h3>\u0415ducation and academic qualifications<\/h3>\n<ul>\n<li style=\"text-align: justify;\">2008 &#8211; Assistant professor, Institute of Plant Physiology and Genetics, Bulgarian Academy of Sciences<\/li>\n<li style=\"text-align: justify;\">2007 PhD in Genetics, Institute of Genetics, Bulgarian Academy of Sciences<\/li>\n<li style=\"text-align: justify;\">1999-2002 PhD student, Institute of Genetics, Bulgarian Academy of Sciences<\/li>\n<li style=\"text-align: justify;\">1997 MSc, Sofia University \u201cSt. Kliment Ohridski,\u201d Faculty of Biology<\/li>\n<\/ul>\n<h3>\u00a0Fellowships and other grants<\/h3>\n<ul>\n<li style=\"text-align: justify;\">International Atomic Energy Agency (IAEA) grant No.: C6\/BUL\/17002, 2017, Project: \u201cMolecular mechanism of seed ageing in barley\u201d Supervisor: Dr. Christopher West, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom<\/li>\n<li style=\"text-align: justify;\">European Molecular Biology Organization (EMBO) award ASTF 261-2008, Project: \u201cEfficiency of backup NHEJ in relation to chromatin structure\u201d, Supervisor: Prof. George Iliakis, Institute of Medical Radiation Biology, University of Duisburg-Essen, Germany<\/li>\n<li style=\"text-align: justify;\">FAO\/IAEA grant for participation in the 6<sup>th<\/sup> Interregional theoretical and practical course \u201eMutant germplasm characterization using molecular markers\u201d, 2006, Plant Breeding and Genetics Unit, Agriculture &amp; Biotechnology Laboratory, Seibersdorf, Austria<\/li>\n<li style=\"text-align: justify;\">ICGEB grant for participation in the theoretical course \u201cGenome dynamics and evolution\u201d 2004, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy.<\/li>\n<li style=\"text-align: justify;\">FESPP grant to attend the XII Congress of the Federation of European Societies of Plant Physiologists (FESPP, August 21\u201325, 2000, Budapest, Hungary)<\/li>\n<\/ul>\n<h3 style=\"text-align: left;\">International training<\/h3>\n<ul>\n<li style=\"text-align: justify;\">Host Laboratory: Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom, Supervisor: Dr. Christopher West, 2017, 3 months<\/li>\n<li style=\"text-align: justify;\">Host Laboratory: Institute of Medical Radiation Biology, University of Duisburg-Essen, Germany, Supervisor: Prof. George Iliakis, &#8211; year 2009 &#8211; 3 months; year 2010 &#8211; 3 months; year 2013 &#8211; 3 months<\/li>\n<li style=\"text-align: justify;\">FAO\/IAEA Agriculture &amp; Biotechnology Laboratory, Seibersdorf, Austria, May-June 2006.<\/li>\n<\/ul>\n<h3>Membership in Scientific Organizations<\/h3>\n<p>Union of Scientists in Bulgaria \u2013 section Genetics<\/p>\n<h3>Supervisory and teaching activities<\/h3>\n<p>Supervisor of two PhD students from IPPG<\/p>\n<p>Supervisor of three master students<\/p>\n<h3>\u00a0Current projects<\/h3>\n<ul>\n<li style=\"text-align: justify;\">IAEA National TC Project BUL5016\u201eImproving the Productivity and Quality of Economically Important Crops through Mutation Breeding and Biotechnology\u201c 2020-2022.<\/li>\n<li style=\"text-align: justify;\">\u041a\u041f-06-\u041d21\/8: \u201eMechanisms of recovery from drought and frost-induced desiccation: strategies for survival of the resurrection plant Haberlea rhodopensis\u201c, 2018-2021. Project coordinator: Prof. Katya Georgieva.<\/li>\n<li style=\"text-align: justify;\">National Research Program: \u201eHealthy nutrition for a strong bioeconomy and quality of life\u201c, 2019-2022. Project coordinator from IPPG \u2013 BAS: Prof. Violeta Velikova.<\/li>\n<li style=\"text-align: justify;\">National Research Program: \u201eEnvironmental protection and reduction of the risk for adverse climate changes\u201c, 2019-2023. Project coordinator from IPPG \u2013 BAS: Prof. Valya Vassileva<\/li>\n<\/ul>\n<h3>\u00a0Main completed projects<\/h3>\n<ul>\n<li style=\"text-align: justify;\">National TC project IAEA-Vienna Bul5014 \u201cScreening of cereal germplasm stress response and adaptation potential by advanced nuclear, omics and physiological approaches\u201d 2016-2017 \u2013 participant<\/li>\n<li style=\"text-align: justify;\">Bulgarian Ministry of Education and Science, \u201cProgram for support of young scientists in BAS\u201d, \u201eEpigenetic modulatory effects of Bulgarian medicinal plant Cotinus coggygria Scop. in human tumor cells in vitro\u201d \u2013 Scientific Supervisor<\/li>\n<li style=\"text-align: justify;\">IAEA-Vienna RC 15481 \u201cIsolation and Characterization of Genes for Radiation Induced DNA Damage Repair in Barley\u201d Part of Co-ordinated Project: \u201cIsolation and Characterization of Genes Involved in Mutagenesis of Crop Plants\u201d 2009-2014 \u2013 Chief Project Investigator<\/li>\n<li style=\"text-align: justify;\">Bulgarian Ministry of Education and Science and European Social Fund BG 051PO001\/07\/ 3.3\u201302\/25\/17.06.2008, 2012-2015 \u2013 participant, scientific supervisor<\/li>\n<li style=\"text-align: justify;\">IAEA-Vienna RER-5\/013 \u201eEvaluation of natural and mutant genetic diversity in cereals using nuclear and molecular techniques\u201d 2007-2011 \u2013 participant<\/li>\n<li style=\"text-align: justify;\">4IAEA-Vienna RC BUL12608 \u201cChromosomal and DNA alterations in barley mutant lines produced by gamma-irradiation\u201d &#8211; CRP \u201cEffects of mutagenic agents on the DNA sequence in plants\u201d 2003-2009 \u2013 participant<\/li>\n<li style=\"text-align: justify;\">Bulgarian Ministry of Education and Science and European Social Fund BG 051PO001\/07\/ 3.3\u201302\/25\/17.06.2008, 2008-2010 \u2013 participant<\/li>\n<li style=\"text-align: justify;\">Bulgarian National Science Fund, Genomics Programme, contract \u2116G-1-01 \u201eFunctional activity and induction of mutational damage in barley genome\u201d 2004-2008\u2013 participant<\/li>\n<\/ul>\n<h3>\u00a0Selected publications<\/h3>\n<p style=\"text-align: justify;\">Gospodinova Z, Krasteva M, Manova V. \u201eEffects of Cotinus coggygria extract on the transcriptional levels of histone deacetylase genes in breast cancer cells in vitro\u201c. American Journal of Pharmacy &amp; Health Research. 2017, 5(8): 60-69.<\/p>\n<p style=\"text-align: justify;\">I. Manova, R. G. Georgieva, B. P. Borisov, L. M. Stoilov \u201cEfficient removal of cyclobutane pyrimidine dimers (CPD) in barley &#8211; differential contribution of light-dependent and dark DNA repair pathways\u201c, Physiologia Plantarum, 158 (2), 236-253, 2016.<\/p>\n<p style=\"text-align: justify;\">Rodeva, Stoyanova Z, Manova V, Georgieva R, Stoilov L. Isolation and characterization of Colletotrichum coccodes from potato in Bulgaria, Acta Horticulturae, 1142, 127-134, 2016<\/p>\n<p style=\"text-align: justify;\">I. Manova, D. Gruszka \u201cDNA damage and repair in plants &#8211; from models to crops\u201d, Frontiers in Plant Science, 6, 885, 2015.<\/p>\n<p style=\"text-align: justify;\">I Nikolova, M Georgieva, K Kruppa, M Moln\u00e1r-L\u00e1ng, K Gecheff, L Liu, V Manova, L. Stoilov Cytogenetic effects in barley root apical meristem after exposure of dry seeds to lithium ion beams. Genetics and Plant Physiology. 5 (1), 3-9, 2015.<\/p>\n<p style=\"text-align: justify;\">V Manova, R. Georgieva, M. Georgieva, I. Nikolova, K. Gecheff, L. Stoilov DNA and chromosomal damage as a hallmark of the induced genomic instability in barley. Genetics and Plant Physiology, 5 (3-4), 231-246, 2015.<\/p>\n<p style=\"text-align: justify;\">M. Stoilov, M. S. Georgieva, V. I. Manova, L. Liu, K. Gecheff \u201cKaryotype reconstruction modulates the sensitivity of barley genome to radiation-induced DNA and chromosomal damage\u201d, Mutagenesis, 28(2), 153, 2013.<\/p>\n<p style=\"text-align: justify;\">I. Manova, S.K. Singh, G. Iliakis \u201cProcessing of DNA double-strand breaks by alternative non-homologous end-joining in hyperacetylated chromatin\u201d, Genome integrity, 3(1), 4, 2012.<\/p>\n<p style=\"text-align: justify;\">I. Manova, M. S. Georgieva, B. P. Borisov, B. Stoilova, K. Gecheff, L. M. Stoilov \u201cGenomic and gene-specific induction and repair of DNA damage in barley\u201d, in \u201cInduced Plant Mutations in the Genomics Era\u201d, Q.Y. Shu (ed.), Food and Agriculture Organization of the United Nations, Rome, 2009, 133.<\/p>\n<p style=\"text-align: justify;\">I. Manova, K. Gecheff, L. M. Stoilov \u201cEfficient repair of bleomycin-induced double-strand breaks in barley ribosomal genes\u201d, Mutation Research, 601, 179, 2006.<\/p>\n<p style=\"text-align: justify;\">I. Manova, L. M. Stoilov \u201cRepair of DNA double-strand breaks in eukaryotic genome\u201d, Genetics and Breeding, 34 (1-2), 39, 2005.<\/p>\n<p style=\"text-align: justify;\">I. Manova, L. M. Stoilov \u201cInduction and recovery of double-strand breaks in barley ribosomal DNA\u201d, DNA repair, 2 (9), 983, 2003.<\/p>\n<h6 style=\"text-align: right;\"><a class=\"_ps2id\" href=\"#top\" data-ps2id-offset=\"300\">[ Top ]<\/a><\/h6>\n","protected":false},"excerpt":{"rendered":"<p>Vasilissa Manova, Assistant Professor, PhD Building 21 Office 106, Lab 211, 221 Phone: +359 (2) 979 2678 \u0415-mail: vmanova@bas.bg Professional interests Molecular mechanisms of plant stress response to DNA damage. Activity and genetic control of DNA repair in plants, Radiation-induced stress response in barley. Molecular mechanisms of seed ageing. Radiation-induced DNA damage and repair in [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":237,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"_links":{"self":[{"href":"http:\/\/www.bio21.bas.bg\/ippg\/en\/index.php?rest_route=\/wp\/v2\/pages\/2364"}],"collection":[{"href":"http:\/\/www.bio21.bas.bg\/ippg\/en\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/www.bio21.bas.bg\/ippg\/en\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/www.bio21.bas.bg\/ippg\/en\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/www.bio21.bas.bg\/ippg\/en\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2364"}],"version-history":[{"count":3,"href":"http:\/\/www.bio21.bas.bg\/ippg\/en\/index.php?rest_route=\/wp\/v2\/pages\/2364\/revisions"}],"predecessor-version":[{"id":2366,"href":"http:\/\/www.bio21.bas.bg\/ippg\/en\/index.php?rest_route=\/wp\/v2\/pages\/2364\/revisions\/2366"}],"up":[{"embeddable":true,"href":"http:\/\/www.bio21.bas.bg\/ippg\/en\/index.php?rest_route=\/wp\/v2\/pages\/237"}],"wp:attachment":[{"href":"http:\/\/www.bio21.bas.bg\/ippg\/en\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2364"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}