|
CURRICULUM VITAE |
||
|
Rumiana Koynova |
|
 |
|
Official Address: 1113 Sofia, Bulgaria |
||
|
tel. (359-2)-979-3685 fax (359-2)-971-2493 E-mail: rkoynova@obzor.bio21.bas.bg |
||
|
|
||
|
CURRICULUM VITAE |
||
|
Rumiana Koynova |
|
|
|
Official Address: 1113 Sofia, Bulgaria |
||
|
tel. (359-2)-979-3685 fax (359-2)-971-2493 E-mail: rkoynova@obzor.bio21.bas.bg |
||
|
|
||
|
Education, Experience, Employment: |
|
|
1976 |
M.S. Solid State Physics, Sofia University, Faculty of Physics |
|
1979 |
M.S. Biophysics, Sofia University, Faculty of Physics |
|
1984 |
Ph.D., Biophysics, Central Laboratory of Biophysics, Bulgarian Academy of Sciences Thesis: "On the Molecular Organization of Two-Component Lipid Bilayers" Graduate Advisor: Prof. Boris Tenchov |
| 2000 |
D.Sc.,
Biophysics, Institute of Biophysics, Bulgarian Academy of
Sciences Thesis: "Regulation of the Phase State of Lipid Membranes" |
|
|
|
|
1984 - 1989 |
Research Associate in 'Model Membranes' Department, Central Laboratory of Biophysics, Bulgarian Academy of Sciences |
|
1989 - present |
Associate Professor of Biophysics Institute of Biophysics, Bulgarian Academy of Sciences |
|
1992 - 1993 |
Visiting Scientist in Chemistry Department The Ohio State University, Columbus, OH, USA Collaboration with Prof. Martin Caffrey |
|
|
|
|
Research fields: structure, thermodynamics and electrical properties of biological membranes; phase transitions in lipid/water systems; phase diagrams of binary mixtures; lipid polymorphism; nonlamellar lipid phases; lamellar - non-lamellar transformations; databases for lipid phase transitions and phase diagrams; mechanisms of membrane damage and cryoprotection; lipid-protein interactions, thermodynamics and stability of proteins |
|
|
Experimental methods: differential scanning calorimetry, X-ray diffraction (static, time-resolved), differential scanning densitometry, fluorescence spectroscopy |
|
|
Other scientific activities: Participation in research projects with foreign laboratories: 'Structure and Thermodynamics of Lyotropic Liquid Crystals' (1987-1990), with Prof. Peter Laggner, Inst. Biophysics & X-Ray Structure Research, Graz, Austria; 'Glycolipids - Synthesis, Structure, Stability. Interactions With Lectins' (1986-1991, 1992-1994), with Prof. Hans-Juergen Hinz, Inst. Biophys. Phys. Biochem., Univ. Regensburg, Germany; 'Membrane Molecular Organization' (1988-1998), with Prof. Peter J. Quinn, Dept. Biomolecular Sciences, King's College London, U.K.; 'Databases for Lipid Phase Transitions and Phase Diagrams', with Prof. Martin Caffrey, Chemistry Department, The Ohio State University, USA; 'Time-resolved X-ray Studies of Lipid/Water Systems' (1996-1999), with Dr. Gert Rapp, EMBL Outstation, and HASYLAB, c/o DESY, Hamburg, Germany; Member of the LIPIDAT & LIPIDAG Databases workgroup; |
|
|
Recent Publications:
|
|
R. Koynova, M. Caffrey Chem. Phys. Lipids 69 (1994) 1-34 Phases and phase transitions of the hydrated phosphatidylethanolamines (review article)
|
|
R. Koynova, M. Caffrey Chem. Phys. Lipids 69 (1994) 181-207 Phases and phase transitions of the glycoglycerolipids (review article)
|
|
S. Taneva, R. Koynova, B. Tenchov FEBS Lett. 345 (1994) 154-158 Thermal stability of lipid-depleted purple membranes at neutral and low pH values
|
|
R. Koynova, M. Caffrey Biochim. Biophys. Acta 1255 (1995) 213-236 Phases and phase transitions of the sphingolipids (review article)
|
|
R. Koynova, B. G. Tenchov, S. Todinova, P. J. Quinn Biophys. J. 68 (1995) 2370-2375 Rapid reversible formation of a metastable subgel phase in saturated diacylphosphatidylcholines
|
|
B. Tenchov, R. Koynova in "Handbook of Non-Medical Applications of Liposomes" (Y. Barenholz, D. Lasic, eds.), CRC Press, 1996, Vol 1, Chapter 10, pp. 237-247. Effect of solutes on the membrane lipid phase behavior
|
|
M. Caffrey, R. Koynova, J. Hogan, D. Moynihan in "Handbook of Non-Medical Applications of Liposomes" (Y. Barenholz, D. Lasic, eds.), CRC Press, 1996, Vol 2, Chapter 6, pp. 85-104. LIPIDAT: A Database of Lipid Phase Transition Temperatures, Enthalpy Changes, and Associated Information
|
|
R. Tenchova, B. Tenchov, H.-J. Hinz, P. J. Quinn Liquid Crystals 20 (1996) 469-482 Lamellar - nonlamellar phase transitions in synthetic glycoglycerolipids studied by time-resolved synchrotron X-ray diffraction
|
|
A. Nikolova, R. Koynova, B. Tenchov and D. Exerowa Chem. Phys. Lipids 83 (2) (1996), 111-121 Chain-melting phase transition in DPPC foam bilayers
|
|
R. Komsa-Penkova, R. Koynova, G. Kostov, B. Tenchov Biochim. Biophys. Acta 1297 (1996) 171-181. Thermal stability of calf skin collagen type I in salt solutions reprint request
|
|
B. Tenchov, M. Rappolt, R. Koynova, G. Rapp Biochim. Biophys. Acta 1285 (1996) 109-122. New phases induced by sucrose in saturated PEs: An expanded lamellar gel phase and a cubic phase
|
|
R. Koynova, A. Koumanov, B. Tenchov Biochim. Biophys. Acta 1285 (1996) 101-108. Metastable rippled gel phase in saturated PCs: calorimetric and densitometric characterization
|
|
R. Koynova, J. Brankov, B. Tenchov Eur. Biophys. J. 25 (1997) 261-275. Modulation of the lipid phase behaviour by kosmotropic and chaotropic solutes reprint request
|
|
Koynova, R., Tenchov, B., Rapp, G. Biochim. Biophys. Acta 1326 (1997) 167-170. Low amounts of PEG-lipid induce cubic phase in phosphatidyl-ethanolamine dispersions reprint request
|
|
R. Koynova, M. Caffrey Biochim. Biophys. Acta 1376 (1998) 91-145 Phases and phase transitions of the phosphatidylcholines (review article) reprint request
|
|
R. Koynova, B. Tenchov, G. Rapp Chem. Phys. Lipids 88 (1997) 45-61. Mixing behavior of saturated short-chain phosphatidylcholines and fatty acids reprint request
|
|
R. Koynova Chem. Phys. Lipids 89 (1997) 67-73 Liquid Crystalline Phase Metastability in Phosphatidylglycerols reprint request
|
|
B. Tenchov, R. Koynova, G. Rapp Biophys. J. 75 (1998) 853-866 Accelerated formation of cubic phases in lipid dispersions reprint request
|
|
B. Tenchov, R. Koynova, M. Rappolt, G. Rapp Biochim. Biophys. Acta 1417 (1999) 183-190 An ordered metastable phase in hydrated phosphatidylethanolamine: the Y-transition reprint request
|
|
R. Koynova, B. Tenchov, G. Rapp Colloids & Surfaces 149 (1999) 571-575 Effect of PEG-lipid conjugates on the phase behavior of phosphatidylethanolamine dispersion reprint request
|
|
L. Alexandrova, R. Koynova, L. Grigorov, B. Tenchov Colloids & Surfaces 149 (1999) 239-244 Singular behavior of the three-phase contact between DMPC dispersion, air and quartz at the critical temperature of 29 °C
|
|
R. Koynova, B. Tenchov, G. Rapp EMBL 1998 Annual Report, pp 491-492 Cubic Phases in Hydrated Lipid Mixtures Containing Cationic Lipids
|
R. Komsa-Penkova, R. Koynova, G. Kostov, B. Tenchov Biophys. Chem. 83:185-195 (1999) Discrete Reduction Of Type I Collagen Thermal Stability Upon Oxidation reprint request
|
| Last modified: Feb 17, 2000 |
Back to Institute of Biophysics
